Custom PDMS Microneedle Mold Fabrication

We provides custom PDMS microneedle mold fabrication services for universities, research institutes, startups, and medical device developers. We support the complete development workflow from master mold fabrication to PDMS replication, enabling rapid prototyping and small-batch production of microneedle devices.

Overview

PDMS (Polydimethylsiloxane) is one of the most widely used materials for microneedle mold fabrication due to its excellent replication fidelity, flexibility, biocompatibility, and ease of processing.

Using high-precision silicon or metal master molds, PDMS can accurately replicate microneedle arrays with micron-scale features, making it ideal for biomedical research, transdermal drug delivery, cosmetic applications, and prototype development.

Our Services

Microneedle Master Mold Fabrication

We fabricate custom master molds using:

• Silicon microneedle masters
• Metal microneedle masters
• Custom microstructured masters
• Positive and negative mold designs

Master molds can be manufactured according to customer drawings or developed collaboratively with our engineering team.

PDMS Microneedle Mold Replication

Our PDMS molding services include:

• Vacuum degassing
• PDMS casting and curing
• Mold release optimization
• Dimensional inspection
• Prototype and low-volume production

Multiple copies can be replicated from a single master mold, making PDMS an economical solution for research and product development.

Microneedle Structures

We support fabrication of:

• Conical microneedles
• Pyramid microneedles
• Hollow microneedles
• Dissolving microneedle molds
• Hydrogel microneedle molds
• Custom geometries

Applications

Drug Delivery

Microneedles enable painless transdermal delivery of vaccines, biologics, peptides, and other therapeutic agents.

Cosmetic Applications

PDMS microneedle molds are commonly used for developing cosmetic patches and skin treatment devices.

Biomedical Research

Applications include:

• Drug screening
• Tissue engineering
• Biosensors
• Wearable devices
• Point-of-care diagnostics

Academic Research

We frequently support university and laboratory projects requiring custom microneedle prototypes and experimental devices.

Why Choose PDMS?

• High replication accuracy
• Excellent feature transfer
• Biocompatibility
• Optical transparency
• Rapid prototyping capability
• Low tooling cost
• Suitable for iterative design development

One-Stop Microneedle Development

In addition to PDMS molding, we also provide:

• Microneedle design review
• Silicon master mold fabrication
• Metal master mold fabrication
• Microfabrication consulting
• Small-batch manufacturing
• Prototype optimization

How to Request a Quote

Please provide:

• CAD drawing or design file
• Microneedle dimensions
• Array size and layout
• Quantity required
• Target application
• Material requirements

Our engineering team will review the project and recommend the most suitable fabrication approach.

Typical Lead Time

Most custom PDMS microneedle mold projects are completed within 2–4 weeks depending on design complexity and production quantity.

Related Services

• Master Mold Fabrication
• Microneedle Master Mold Fabrication
• PDMS Molding Service
• Soft Lithography
• Silicon Microfabrication
• Biomedical Device Prototyping